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Pathophysio - Morbidity of sickle cell disease

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This paragraph is only a very schematic overview of a complex clinical situation, varying considerably from one patient to another.

In individuals with sickle cell disease, the triggering mechanism of the pathological manifestations is the polymerization of HbS in red blood cells upon deoxygenation.

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http://rbc.gs-im3.fr/DATA/The%20HW_CD/EnglDrepanoPatho.html

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